Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1

Structural genomics approach to investigate deleterious impact of nsSNPs in conserved telomere maintenance component 1

Abstract Conserved telomere maintenance component 1 (CTC1) is an important component of the CST (CTC1-STN1-TEN1) complex, involved in maintaining the stability of telomeric DNA. Several non-synonymous single-nucleotide polymorphisms (nsSNPs) in CTC1 have been reported to cause Coats plus syndrome an...

Full description

Saved in:
Bibliographic Details
Main Authors: Arunabh Choudhury, Taj Mohammad, Nikhil Samarth, Afzal Hussain, Md. Tabish Rehman, Asimul Islam, Mohamed F. Alajmi, Shailza Singh, Md. Imtaiyaz Hassan
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/778ff0f482034cf3800d06584dcf9a28
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items