Multipotent adult progenitor cells induce regulatory T cells and promote their suppressive phenotype via TGFβ and monocyte-dependent mechanisms

Abstract Dysregulation of the immune system can initiate chronic inflammatory responses that exacerbate disease pathology. Multipotent adult progenitor cells (MAPC cells), an adult adherent bone-marrow derived stromal cell, have been observed to promote the resolution of uncontrolled inflammatory re...

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Autores principales: Alice Valentin-Torres, Cora Day, Jennifer M. Taggart, Nicholas Williams, Samantha R. Stubblefield, Valerie D. Roobrouck, Jelle Beyens, Anthony E. Ting
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/779477ab8c53409695514d59b74870eb
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