XX sex chromosome complement promotes atherosclerosis in mice

Men and women differ in their risk of developing coronary artery disease, in part due to differences in their levels of sex hormones. Here, AlSiraj et al. show that the XX sex genotype regulates lipid metabolism and promotes atherosclerosis independently of sex hormones in mice.

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Detalles Bibliográficos
Autores principales:	Yasir AlSiraj, Xuqi Chen, Sean E. Thatcher, Ryan E. Temel, Lei Cai, Eric Blalock, Wendy Katz, Heba M. Ali, Michael Petriello, Pan Deng, Andrew J. Morris, Xuping Wang, Aldons J. Lusis, Arthur P. Arnold, Karen Reue, Katherine Thompson, Patrick Tso, Lisa A. Cassis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/779e3daba0e549a3b1b7cf483d20172c
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spelling	oai:doaj.org-article:779e3daba0e549a3b1b7cf483d20172c2021-12-02T14:39:36ZXX sex chromosome complement promotes atherosclerosis in mice10.1038/s41467-019-10462-z2041-1723https://doaj.org/article/779e3daba0e549a3b1b7cf483d20172c2019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10462-zhttps://doaj.org/toc/2041-1723Men and women differ in their risk of developing coronary artery disease, in part due to differences in their levels of sex hormones. Here, AlSiraj et al. show that the XX sex genotype regulates lipid metabolism and promotes atherosclerosis independently of sex hormones in mice.Yasir AlSirajXuqi ChenSean E. ThatcherRyan E. TemelLei CaiEric BlalockWendy KatzHeba M. AliMichael PetrielloPan DengAndrew J. MorrisXuping WangAldons J. LusisArthur P. ArnoldKaren ReueKatherine ThompsonPatrick TsoLisa A. CassisNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yasir AlSiraj Xuqi Chen Sean E. Thatcher Ryan E. Temel Lei Cai Eric Blalock Wendy Katz Heba M. Ali Michael Petriello Pan Deng Andrew J. Morris Xuping Wang Aldons J. Lusis Arthur P. Arnold Karen Reue Katherine Thompson Patrick Tso Lisa A. Cassis XX sex chromosome complement promotes atherosclerosis in mice
description	Men and women differ in their risk of developing coronary artery disease, in part due to differences in their levels of sex hormones. Here, AlSiraj et al. show that the XX sex genotype regulates lipid metabolism and promotes atherosclerosis independently of sex hormones in mice.
format	article
author	Yasir AlSiraj Xuqi Chen Sean E. Thatcher Ryan E. Temel Lei Cai Eric Blalock Wendy Katz Heba M. Ali Michael Petriello Pan Deng Andrew J. Morris Xuping Wang Aldons J. Lusis Arthur P. Arnold Karen Reue Katherine Thompson Patrick Tso Lisa A. Cassis
author_facet	Yasir AlSiraj Xuqi Chen Sean E. Thatcher Ryan E. Temel Lei Cai Eric Blalock Wendy Katz Heba M. Ali Michael Petriello Pan Deng Andrew J. Morris Xuping Wang Aldons J. Lusis Arthur P. Arnold Karen Reue Katherine Thompson Patrick Tso Lisa A. Cassis
author_sort	Yasir AlSiraj
title	XX sex chromosome complement promotes atherosclerosis in mice
title_short	XX sex chromosome complement promotes atherosclerosis in mice
title_full	XX sex chromosome complement promotes atherosclerosis in mice
title_fullStr	XX sex chromosome complement promotes atherosclerosis in mice
title_full_unstemmed	XX sex chromosome complement promotes atherosclerosis in mice
title_sort	xx sex chromosome complement promotes atherosclerosis in mice
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/779e3daba0e549a3b1b7cf483d20172c
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XX sex chromosome complement promotes atherosclerosis in mice

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