EphA2 Expression in Bone Sarcomas: Bioinformatic Analyses and Preclinical Characterization in Patient-Derived Models of Osteosarcoma, Ewing’s Sarcoma and Chondrosarcoma

EphA2 Expression in Bone Sarcomas: Bioinformatic Analyses and Preclinical Characterization in Patient-Derived Models of Osteosarcoma, Ewing’s Sarcoma and Chondrosarcoma

Bone sarcomas are a group of heterogeneous malignant mesenchymal tumors. Complete surgical resection is still the cornerstone of treatment, but, in the advanced/unresectable setting, their management remains challenging and not significantly improved by target- and immuno-therapies. We focused on th...

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Main Authors: Giorgia Giordano, Alessandra Merlini, Giulio Ferrero, Giulia Mesiano, Erika Fiorino, Silvia Brusco, Maria Laura Centomo, Valeria Leuci, Lorenzo D’Ambrosio, Massimo Aglietta, Dario Sangiolo, Giovanni Grignani, Ymera Pignochino
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
target therapies
bioinformatics
EphA2
osteosarcoma
Ewing’s sarcoma
chondrosarcoma
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/779f34e736fa4de89f800e07e0ab3ebf
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https://doaj.org/article/779f34e736fa4de89f800e07e0ab3ebf

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