The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19

ABSTRACT The coronavirus disease 2019 (COVID-19) pandemic has caused significant morbidity and mortality on a global scale. The etiologic agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), initiates host cell entry when its spike protein (S) binds to its receptor, angiotensin-conve...

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Bibliographic Details
Main Authors: Kun Li, David K. Meyerholz, Jennifer A. Bartlett, Paul B. McCray
Format: article
Language:EN
Published: American Society for Microbiology 2021
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Online Access:https://doaj.org/article/77e6b0a301cb4b8092445ca9e3ad6c99
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