Evolutionary dynamics on protein bi-stability landscapes can potentially resolve adaptive conflicts.

Experimental studies have shown that some proteins exist in two alternative native-state conformations. It has been proposed that such bi-stable proteins can potentially function as evolutionary bridges at the interface between two neutral networks of protein sequences that fold uniquely into the tw...

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Autores principales: Tobias Sikosek, Erich Bornberg-Bauer, Hue Sun Chan
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/7804b5e0bc924cbc96dff707ea25db22
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