A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy

A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy

Abstract Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors. We examined the renoprotective effects of Ly, a novel non-steroidal mineralocorticoid receptor (MR) blocker, through two ex...

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Main Authors: Clarice K. Fujihara, M. C. Kowala, M. D. Breyer, Claudia R. Sena, Mariliza V. Rodrigues, Simone C. A. Arias, Camilla Fanelli, Denise M. Malheiros, P. K. Jadhav, Chahrzad Montrose-Rafizadeh, Jose E. Krieger, Roberto Zatz
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/780f96a202214d06a07005c8f676b540
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https://doaj.org/article/780f96a202214d06a07005c8f676b540

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