A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy

A Novel Aldosterone Antagonist Limits Renal Injury in 5/6 Nephrectomy

Abstract Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors. We examined the renoprotective effects of Ly, a novel non-steroidal mineralocorticoid receptor (MR) blocker, through two ex...

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Autores principales: Clarice K. Fujihara, M. C. Kowala, M. D. Breyer, Claudia R. Sena, Mariliza V. Rodrigues, Simone C. A. Arias, Camilla Fanelli, Denise M. Malheiros, P. K. Jadhav, Chahrzad Montrose-Rafizadeh, Jose E. Krieger, Roberto Zatz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/780f96a202214d06a07005c8f676b540
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