Sprouty4 negatively regulates ERK/MAPK signaling and the transition from in situ to invasive breast ductal carcinoma.

Breast ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal carcinoma (IDC). It is still unclear which DCIS will become invasive and which will remain indolent. Patients often receive surgery and radiotherapy, but this early intervention has not produced substantial decreas...

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Auteurs principaux: Ethan J Brock, Ryan M Jackson, Julie L Boerner, Quanwen Li, Meredith A Tennis, Bonnie F Sloane, Raymond R Mattingly
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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R
Q
Accès en ligne:https://doaj.org/article/782395728add4407ae876509cd7124b3
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