Noncanonical Inhibition of mTORC1 by <named-content content-type="genus-species">Coxiella burnetii</named-content> Promotes Replication within a Phagolysosome-Like Vacuole

ABSTRACT The Q fever agent Coxiella burnetii is a Gram-negative bacterium that invades macrophages and replicates inside a specialized lysosomal vacuole. The pathogen employs a type 4B secretion system (T4BSS) to deliver effector proteins into the host cell that modify the Coxiella-containing vacuol...

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Autores principales: Charles L. Larson, Kelsi M. Sandoz, Diane C. Cockrell, Robert A. Heinzen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/7824023c2cc14cbab101e8b0c9e102eb
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