Preclinical Evaluation of Polymeric Nanocomposite Containing Pregabalin for Sustained Release as Potential Therapy for Neuropathic Pain
This study offers a novel oral pregabalin (PG)-loaded drug delivery system based on chitosan and hypromellose phthalate-based polymeric nanocomposite in order to treat neuropathic pain (PG-PN). PG-PN has a particle size of 432 ± 20 nm, a polydispersity index of 0.238 ± 0.001, a zeta potential of +19...
Guardado en:
Autores principales: | Rafaela Figueiredo Rodrigues, Juliana Barbosa Nunes, Sandra Barbosa Neder Agostini, Paloma Freitas dos Santos, Juliana Cancino-Bernardi, Rodrigo Vicentino Placido, Thamyris Reis Moraes, Jennifer Tavares Jacon Freitas, Gislaine Ribeiro Pereira, Flávia Chiva Carvalho, Giovane Galdino, Vanessa Bergamin Boralli |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7829cca9daee4d8e95b7582b1cae90af |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Treatment of postherpetic neuralgia: focus on pregabalin
por: Kimberly A Cappuzzo
Publicado: (2008) -
VALIDATED STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF NORTRIPTYLINE AND PREGABALIN IN BULK AND COMBINED DOSAGE FORMULATIONS
por: POTLURI,HARITHA, et al.
Publicado: (2017) -
EFFECT OF SINGLE-DOSE PREGABALIN ON POSTOPERATIVE PAIN IN DACRYOCYSTORHINOSTOMY SURGERY
por: Sana Abbas, et al.
Publicado: (2021) -
Resistance Exercise and Whey Protein Supplementation Reduce Mechanical Allodynia and Spinal Microglia Activation After Acute Muscle Trauma in Rats
por: Gusthavo Rodrigues, et al.
Publicado: (2021) -
Heterogeneity in diabetic distal neuropathy and differential approach to its treatment
por: Oksana Evgen'evna Khutornaya, et al.
Publicado: (2013)