Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination
Alternative end joining (A-EJ) catalyzes substantial level of antibody class switch recombination (CSR) in B cells deficient for classical non-homologous end joining, featuring increased switch (S) region DSB resection and junctional microhomology (MH). While resection has been suggested to initiate...
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Autores principales: | , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://doaj.org/article/783e94bec6534c0ba59ab903e0bf080f |
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