Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects
A challenge in regenerative medicine is the development of cell-free, non-immunogenic miRNA-delivering scaffolds. Here the authors design a cell-free scaffold capable of efficient and prolonged delivery of miRNA-26a to endogenous cells and show that it can regenerate a full-thickness calvarial bone...
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Main Authors: | Xiaojin Zhang, Yan Li, Y. Eugene Chen, Jihua Chen, Peter X. Ma |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2016
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Subjects: | |
Online Access: | https://doaj.org/article/783ff9bf6ea14f57b75bbdaad033b2ec |
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