Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth
Thymic epithelial cells (TEC) are essential for the maturation of functional T cells, while thymus size is proportional to the overall output efficiency. Here the authors show, using transcriptome analyses, that mouse fetal TEC maintain a Myc-dependent genetic program to ensure a rapid increase in t...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Nature Portfolio
2019
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Accès en ligne: | https://doaj.org/article/784327815c984356aac217a9fbd2ed1e |
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