DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis
DNA polymerase epsilon (Pol ε) synthesizes half of the genome in every cell cycle. Here the authors uncover a dual role of a unique domain within the Pol ε catalytic core in replisome assembly and DNA synthesis and the impact of this domain on genome stability.
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/784f3f5d0e034b3d9506e9710237067b |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|