Angiopoietin-like 4 induces a β-catenin-mediated upregulation of ID3 in fibroblasts to reduce scar collagen expression

Abstract In adult skin wounds, collagen expression rapidly re-establishes the skin barrier, although the resultant scar is aesthetically and functionally inferior to unwounded tissue. Although TGFβ signaling and fibroblasts are known to be responsible for scar-associated collagen production, there a...

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Autores principales: Ziqiang Teo, Jeremy Soon Kiat Chan, Han Chung Chong, Ming Keat Sng, Chee Chong Choo, Glendon Zhi Ming Phua, Daniel Jin Rong Teo, Pengcheng Zhu, Cleo Choong, Marcus Thien Chong Wong, Nguan Soon Tan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7887f24654604d11834355e7bd5e1492
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