Caffeine-inducible gene switches controlling experimental diabetes
Control of transgene expression should ideally be easy and with minimal side effects. Here the authors present a synthetic biology-based approach in which the caffeine in coffee regulates a genetic circuit controlling glucagon-like peptide 1 expression in diabetic mice.
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Auteurs principaux: | Daniel Bojar, Leo Scheller, Ghislaine Charpin-El Hamri, Mingqi Xie, Martin Fussenegger |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2018
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Sujets: | |
Accès en ligne: | https://doaj.org/article/78897e8e6b274e48b9f08daab11ccd6a |
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