Selective Inhibition of <i>Helicobacter pylori</i> Carbonic Anhydrases by Carvacrol and Thymol Could Impair Biofilm Production and the Release of Outer Membrane Vesicles

Selective Inhibition of <i>Helicobacter pylori</i> Carbonic Anhydrases by Carvacrol and Thymol Could Impair Biofilm Production and the Release of Outer Membrane Vesicles

<i>Helicobacter pylori</i>, a Gram-negative neutrophilic pathogen, is the cause of chronic gastritis, peptic ulcers, and gastric cancer in humans. Current therapeutic regimens suffer from an emerging bacterial resistance rate and poor patience compliance. To improve the discovery of comp...

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Bibliographic Details
Main Authors: Rossella Grande, Simone Carradori, Valentina Puca, Irene Vitale, Andrea Angeli, Alessio Nocentini, Alessandro Bonardi, Paola Gratteri, Paola Lanuti, Giuseppina Bologna, Pasquale Simeone, Clemente Capasso, Viviana De Luca, Claudiu T. Supuran
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
carvacrol
thymol
<i>Helicobacter pylori</i>
carbonic anhydrase
anti-biofilm activity
molecular modelling
Biology (General)
QH301-705.5
Chemistry
QD1-999
Online Access:https://doaj.org/article/788d8632b6134443956253ad8d206eff
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https://doaj.org/article/788d8632b6134443956253ad8d206eff

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