Control of <italic toggle="yes">gdhR</italic> Expression in <italic toggle="yes">Neisseria gonorrhoeae</italic> via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon

Control of <italic toggle="yes">gdhR</italic> Expression in <italic toggle="yes">Neisseria gonorrhoeae</italic> via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon

ABSTRACT The MtrCDE efflux pump of Neisseria gonorrhoeae contributes to gonococcal resistance to a number of antibiotics used previously or currently in treatment of gonorrhea, as well as to host-derived antimicrobials that participate in innate defense. Overexpression of the MtrCDE efflux pump incr...

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Autores principales: Corinne E. Rouquette-Loughlin, Yaramah M. Zalucki, Vijaya L. Dhulipala, Jacqueline T. Balthazar, Raúl G. Doyle, Robert A. Nicholas, Afrin A. Begum, Erica L. Raterman, Ann E. Jerse, William M. Shafer
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
Materias:
gonococci
transcription
efflux pumps
physiology
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/78a52acdff2b4e739aa56bb2bf870f78
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