Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion

Senoo et al. describe a chemical fragment that disrupts dimerization of P-cadherin. In doing so, this fragment inhibits cadherin-mediated cell-adhesion and aggregation.

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Autores principales:	Akinobu Senoo, Sho Ito, Satoru Nagatoishi, Yutaro Saito, Go Ueno, Daisuke Kuroda, Kouhei Yoshida, Takumi Tashima, Shota Kudo, Shinsuke Sando, Kouhei Tsumoto
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/78b79e1b2b4e4736a8a8908c4e78773c
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spelling	oai:doaj.org-article:78b79e1b2b4e4736a8a8908c4e78773c2021-12-02T17:19:12ZRegulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion10.1038/s42003-021-02575-32399-3642https://doaj.org/article/78b79e1b2b4e4736a8a8908c4e78773c2021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02575-3https://doaj.org/toc/2399-3642Senoo et al. describe a chemical fragment that disrupts dimerization of P-cadherin. In doing so, this fragment inhibits cadherin-mediated cell-adhesion and aggregation.Akinobu SenooSho ItoSatoru NagatoishiYutaro SaitoGo UenoDaisuke KurodaKouhei YoshidaTakumi TashimaShota KudoShinsuke SandoKouhei TsumotoNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Akinobu Senoo Sho Ito Satoru Nagatoishi Yutaro Saito Go Ueno Daisuke Kuroda Kouhei Yoshida Takumi Tashima Shota Kudo Shinsuke Sando Kouhei Tsumoto Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
description	Senoo et al. describe a chemical fragment that disrupts dimerization of P-cadherin. In doing so, this fragment inhibits cadherin-mediated cell-adhesion and aggregation.
format	article
author	Akinobu Senoo Sho Ito Satoru Nagatoishi Yutaro Saito Go Ueno Daisuke Kuroda Kouhei Yoshida Takumi Tashima Shota Kudo Shinsuke Sando Kouhei Tsumoto
author_facet	Akinobu Senoo Sho Ito Satoru Nagatoishi Yutaro Saito Go Ueno Daisuke Kuroda Kouhei Yoshida Takumi Tashima Shota Kudo Shinsuke Sando Kouhei Tsumoto
author_sort	Akinobu Senoo
title	Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
title_short	Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
title_full	Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
title_fullStr	Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
title_full_unstemmed	Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
title_sort	regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/78b79e1b2b4e4736a8a8908c4e78773c
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Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion

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