<i>Nox</i>2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis

Osteoarthritis (OA) is a destructive disease of the joint with age and obesity being its most important risk factors. Around 50% of OA patients suffer from inflammation of the synovial joint capsule, which is characterized by increased abundance and activation of synovial macrophages that produce re...

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Bibliographic Details
Main Authors:	Nik N. L. Kruisbergen, Irene Di Ceglie, Yvonne van Gemert, Birgitte Walgreen, Monique M. A. Helsen, Annet W. Slöetjes, Marije I. Koenders, Fons A. J. van de Loo, Johannes Roth, Thomas Vogl, Peter M. van der Kraan, Arjen B. Blom, Peter L. E. M. van Lent, Martijn H. J. van den Bosch
Format:	article
Language:	EN
Published:	MDPI AG 2021
Subjects:	osteoarthritis ROS Macrophages NOX2 low-density lipoprotein Therapeutics. Pharmacology RM1-950
Online Access:	https://doaj.org/article/78cf3de17a744173a88dbeea58163c1d
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<i>Nox</i>2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis

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