Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics

Mitochondria are a hub that can direct cellular outcomes in response to stress. Here, the authors show that mitochondrial phosphatase PGAM5 has a role in mitochondrial turnover and regulation of cellular senescence by altering organellar dynamics via fission regulator Drp1.

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Autores principales: Bo Yu, Jing Ma, Jing Li, Dazhi Wang, Zhigao Wang, Shusheng Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/78f439af309a43a889952c8065a38027
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