Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice.

Hepatitis C virus (HCV) is the etiologic agent of chronic liver disease, hepatitis C. Spontaneous resolution of viral infection is associated with vigorous HLA class I- and class II-restricted T cell responses to multiple viral epitopes. Unfortunately, only 20% of patients clear infection spontaneou...

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Autores principales: Sasmita Mishra, Bianca J Lavelle, Joe Desrosiers, Matt T Ardito, Frances Terry, William D Martin, Anne S De Groot, Stephen H Gregory
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/78fef72019b7414c8b303e05f3f57ca0
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