Comparative validation of three DNA methylation algorithms of ageing and a frailty index in relation to mortality: results from the ESTHER cohort study

Background: Three DNA methylation (DNAm) based algorithms, DNAm PhenoAge acceleration (AgeAccelPheno), DNAm GrimAge acceleration (AgeAccelGrim), and mortality risk score (MRscore), based on methylation in 513, 1030, and 10 CpGs, respectively, were established to predict health outcomes and mortality...

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Autores principales: Xiangwei Li, Yan Zhang, Xīn Gào, Bernd Holleczek, Ben Schöttker, Hermann Brenner
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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R
Acceso en línea:https://doaj.org/article/7904ed83a0ae423b8f72ea9ab9e56186
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