Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration

The development of conjugate boryl addition to α,β-unsaturated amide has been hampered by the intrinsic low electrophilicity of the amide group. Here the authors show a catalytic asymmetric synthesis of enantioenriched tertiary boronic esters through hydroboration of β,β-disubstituted α,β-unsaturate...

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Autores principales:	Tao-Tao Gao, Hou-Xiang Lu, Peng-Chao Gao, Bi-Jie Li
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/79062422f6d14c12871cc6a57055e2f7
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spelling	oai:doaj.org-article:79062422f6d14c12871cc6a57055e2f72021-12-02T16:04:21ZEnantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration10.1038/s41467-021-24012-z2041-1723https://doaj.org/article/79062422f6d14c12871cc6a57055e2f72021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24012-zhttps://doaj.org/toc/2041-1723The development of conjugate boryl addition to α,β-unsaturated amide has been hampered by the intrinsic low electrophilicity of the amide group. Here the authors show a catalytic asymmetric synthesis of enantioenriched tertiary boronic esters through hydroboration of β,β-disubstituted α,β-unsaturated amides.Tao-Tao GaoHou-Xiang LuPeng-Chao GaoBi-Jie LiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tao-Tao Gao Hou-Xiang Lu Peng-Chao Gao Bi-Jie Li Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration
description	The development of conjugate boryl addition to α,β-unsaturated amide has been hampered by the intrinsic low electrophilicity of the amide group. Here the authors show a catalytic asymmetric synthesis of enantioenriched tertiary boronic esters through hydroboration of β,β-disubstituted α,β-unsaturated amides.
format	article
author	Tao-Tao Gao Hou-Xiang Lu Peng-Chao Gao Bi-Jie Li
author_facet	Tao-Tao Gao Hou-Xiang Lu Peng-Chao Gao Bi-Jie Li
author_sort	Tao-Tao Gao
title	Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration
title_short	Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration
title_full	Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration
title_fullStr	Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration
title_full_unstemmed	Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration
title_sort	enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/79062422f6d14c12871cc6a57055e2f7
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Enantioselective synthesis of tertiary boronic esters through catalytic asymmetric reversed hydroboration

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