Pd-catalysed ligand-enabled carboxylate-directed highly regioselective arylation of aliphatic acids

Palladium catalysed C-H functionalization ofsp3carbons typically requires the installation and subsequent removal of a temporary directing group. Here the authors report a method allowing C-H functionalization in carboxylic acids in which the carboxylate acts as a directing group.

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Autores principales: Yan Zhu, Xiaolan Chen, Chunchen Yuan, Guobao Li, Jingyu Zhang, Yingsheng Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Q
Acceso en línea:https://doaj.org/article/79d36e5bbcad49988d35ee9fadc52393
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