Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists <named-content content-type="genus-species">Rhodobacter sphaeroides</named-content> Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2
ABSTRACT Respiratory syncytial virus (RSV) is a leading cause of infant mortality worldwide. Toll-like receptor 4 (TLR4), a signaling receptor for structurally diverse microbe-associated molecular patterns, is activated by the RSV fusion (F) protein and by bacterial lipopolysaccharide (LPS) in a CD1...
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Autores principales: | , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2012
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Acceso en línea: | https://doaj.org/article/79ea6ff9ae2848cdaa97e9031ac10480 |
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