Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists <named-content content-type="genus-species">Rhodobacter sphaeroides</named-content> Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2

Respiratory Syncytial Virus Fusion Protein-Induced Toll-Like Receptor 4 (TLR4) Signaling Is Inhibited by the TLR4 Antagonists <named-content content-type="genus-species">Rhodobacter sphaeroides</named-content> Lipopolysaccharide and Eritoran (E5564) and Requires Direct Interaction with MD-2

ABSTRACT Respiratory syncytial virus (RSV) is a leading cause of infant mortality worldwide. Toll-like receptor 4 (TLR4), a signaling receptor for structurally diverse microbe-associated molecular patterns, is activated by the RSV fusion (F) protein and by bacterial lipopolysaccharide (LPS) in a CD1...

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Autores principales: Prasad Rallabhandi, Rachel L. Phillips, Marina S. Boukhvalova, Lioubov M. Pletneva, Kari Ann Shirey, Theresa L. Gioannini, Jerrold P. Weiss, Jesse C. Chow, Lynn D. Hawkins, Stefanie N. Vogel, Jorge C. G. Blanco
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2012
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/79ea6ff9ae2848cdaa97e9031ac10480
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