Structural dynamics of human telomeric G-quadruplex loops studied by molecular dynamics simulations.

Loops which are linkers connecting G-strands and supporting the G-tetrad core in G-quadruplex are important for biological roles of G-quadruplexes. TTA loop is a common sequence which mainly resides in human telomeric DNA (hTel) G-quadruplex. A series of molecular dynamics (MD) simulations were carr...

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Autores principales: Hong Zhu, Shiyan Xiao, Haojun Liang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/79eb64632fad471db5b923427a906540
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