Structural dynamics of human telomeric G-quadruplex loops studied by molecular dynamics simulations.
Loops which are linkers connecting G-strands and supporting the G-tetrad core in G-quadruplex are important for biological roles of G-quadruplexes. TTA loop is a common sequence which mainly resides in human telomeric DNA (hTel) G-quadruplex. A series of molecular dynamics (MD) simulations were carr...
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Autores principales: | Hong Zhu, Shiyan Xiao, Haojun Liang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/79eb64632fad471db5b923427a906540 |
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