Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine

The ChAdOx1 nCoV-19 vaccine requires two doses, but under limited supply single dose regimens have also been considered. Here, the authors show using static transmission modelling that under certain conditions it is optimal to more expediently administer a single dose to a larger proportion of the p...

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Autores principales: Ricardo Aguas, Anouska Bharath, Lisa J. White, Bo Gao, Andrew J. Pollard, Merryn Voysey, Rima Shretta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7a0e0cd06c084d2f86ddfa12e23c4a2e
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spelling oai:doaj.org-article:7a0e0cd06c084d2f86ddfa12e23c4a2e2021-11-08T11:07:53ZPotential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine10.1038/s41467-021-26449-82041-1723https://doaj.org/article/7a0e0cd06c084d2f86ddfa12e23c4a2e2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26449-8https://doaj.org/toc/2041-1723The ChAdOx1 nCoV-19 vaccine requires two doses, but under limited supply single dose regimens have also been considered. Here, the authors show using static transmission modelling that under certain conditions it is optimal to more expediently administer a single dose to a larger proportion of the population.Ricardo AguasAnouska BharathLisa J. WhiteBo GaoAndrew J. PollardMerryn VoyseyRima ShrettaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ricardo Aguas
Anouska Bharath
Lisa J. White
Bo Gao
Andrew J. Pollard
Merryn Voysey
Rima Shretta
Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
description The ChAdOx1 nCoV-19 vaccine requires two doses, but under limited supply single dose regimens have also been considered. Here, the authors show using static transmission modelling that under certain conditions it is optimal to more expediently administer a single dose to a larger proportion of the population.
format article
author Ricardo Aguas
Anouska Bharath
Lisa J. White
Bo Gao
Andrew J. Pollard
Merryn Voysey
Rima Shretta
author_facet Ricardo Aguas
Anouska Bharath
Lisa J. White
Bo Gao
Andrew J. Pollard
Merryn Voysey
Rima Shretta
author_sort Ricardo Aguas
title Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_short Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_full Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_fullStr Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_full_unstemmed Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_sort potential global impacts of alternative dosing regimen and rollout options for the chadox1 ncov-19 vaccine
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/7a0e0cd06c084d2f86ddfa12e23c4a2e
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