Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine

The ChAdOx1 nCoV-19 vaccine requires two doses, but under limited supply single dose regimens have also been considered. Here, the authors show using static transmission modelling that under certain conditions it is optimal to more expediently administer a single dose to a larger proportion of the p...

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Main Authors:	Ricardo Aguas, Anouska Bharath, Lisa J. White, Bo Gao, Andrew J. Pollard, Merryn Voysey, Rima Shretta
Format:	article
Language:	EN
Published:	Nature Portfolio 2021
Subjects:	Science Q
Online Access:	https://doaj.org/article/7a0e0cd06c084d2f86ddfa12e23c4a2e
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spelling	oai:doaj.org-article:7a0e0cd06c084d2f86ddfa12e23c4a2e2021-11-08T11:07:53ZPotential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine10.1038/s41467-021-26449-82041-1723https://doaj.org/article/7a0e0cd06c084d2f86ddfa12e23c4a2e2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26449-8https://doaj.org/toc/2041-1723The ChAdOx1 nCoV-19 vaccine requires two doses, but under limited supply single dose regimens have also been considered. Here, the authors show using static transmission modelling that under certain conditions it is optimal to more expediently administer a single dose to a larger proportion of the population.Ricardo AguasAnouska BharathLisa J. WhiteBo GaoAndrew J. PollardMerryn VoyseyRima ShrettaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ricardo Aguas Anouska Bharath Lisa J. White Bo Gao Andrew J. Pollard Merryn Voysey Rima Shretta Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
description	The ChAdOx1 nCoV-19 vaccine requires two doses, but under limited supply single dose regimens have also been considered. Here, the authors show using static transmission modelling that under certain conditions it is optimal to more expediently administer a single dose to a larger proportion of the population.
format	article
author	Ricardo Aguas Anouska Bharath Lisa J. White Bo Gao Andrew J. Pollard Merryn Voysey Rima Shretta
author_facet	Ricardo Aguas Anouska Bharath Lisa J. White Bo Gao Andrew J. Pollard Merryn Voysey Rima Shretta
author_sort	Ricardo Aguas
title	Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_short	Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_full	Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_fullStr	Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_full_unstemmed	Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine
title_sort	potential global impacts of alternative dosing regimen and rollout options for the chadox1 ncov-19 vaccine
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7a0e0cd06c084d2f86ddfa12e23c4a2e
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Potential global impacts of alternative dosing regimen and rollout options for the ChAdOx1 nCoV-19 vaccine

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