Aberrant Mitochondrial Dynamics and Exacerbated Response to Neuroinflammation in a Novel Mouse Model of CMT2A

Charcot-Marie-Tooth disease type 2A (CMT2A) is the most common hereditary axonal neuropathy caused by mutations in <i>MFN2</i> encoding Mitofusin-2, a multifunctional protein located in the outer mitochondrial membrane. In order to study the effects of a novel <i>MFN2<sup>K35...

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Autores principales: Filippos Stavropoulos, Irene Sargiannidou, Louiza Potamiti, Alexia Kagiava, Mihalis I. Panayiotidis, Ji Hyun Bae, Su Cheong Yeom, Jae Young Lee, Kleopas A. Kleopa
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/7a19fa7087544b0ab83ac09a7ccee5ab
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