Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice.

Controlling intestinal lipid absorption is an important strategy for maintaining lipid homeostasis. Accumulation of lipids in the liver is a major risk factor for metabolic syndrome and nonalcoholic fatty liver disease. It is well-known that sphingomyelin (SM) can inhibit intestinal cholesterol abso...

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Bibliographic Details
Main Authors: Rosanna W S Chung, Alvin Kamili, Sally Tandy, Jacquelyn M Weir, Raj Gaire, Gerard Wong, Peter J Meikle, Jeffrey S Cohn, Kerry-Anne Rye
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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R
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Online Access:https://doaj.org/article/7a233ffbf308413ba71efb174983cd7f
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