Dietary sphingomyelin lowers hepatic lipid levels and inhibits intestinal cholesterol absorption in high-fat-fed mice.
Controlling intestinal lipid absorption is an important strategy for maintaining lipid homeostasis. Accumulation of lipids in the liver is a major risk factor for metabolic syndrome and nonalcoholic fatty liver disease. It is well-known that sphingomyelin (SM) can inhibit intestinal cholesterol abso...
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Autores principales: | Rosanna W S Chung, Alvin Kamili, Sally Tandy, Jacquelyn M Weir, Raj Gaire, Gerard Wong, Peter J Meikle, Jeffrey S Cohn, Kerry-Anne Rye |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/7a233ffbf308413ba71efb174983cd7f |
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