Adenosine A2A receptor signaling promotes FoxO associated autophagy in chondrocytes

Abstract Autophagy, a homeostatic pathway upregulated during cellular stress, is decreased in osteoarthritic chondrocytes and this reduction in autophagy is thought to contribute to the development and progression of osteoarthritis (OA). The adenosine A2A receptor (A2AR) is a potent anti-inflammator...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Benjamin Friedman, Carmen Corciulo, Cristina M. Castro, Bruce N. Cronstein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/7a28cadbee7746b4b032c27613f2cde2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!