Identification of the organic anion transporting polypeptides responsible for the hepatic uptake of the major metabolite of epyrifenacil, S‐3100‐CA, in mice

Abstract Epyrifenacil is a novel herbicide that acts as an inhibitor of protoporphyrinogen oxidase (PPO) and produces hepatotoxicity in rodents by inhibiting PPO. Our previous research revealed that the causal substance of hepatotoxicity is S‐3100‐CA, a major metabolite of epyrifenacil, and that hum...

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Auteurs principaux: Kengo Sakurai, Tomohiro Kuroda, Jun Abe, Hiroshi Toda, Sachiko Kitamoto
Format: article
Langue:EN
Publié: Wiley 2021
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Accès en ligne:https://doaj.org/article/7a3eacb68306478f8d36c9eaa9956cf8
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