Essential role of MED1 in the transcriptional regulation of ER-dependent oncogenic miRNAs in breast cancer

Abstract Mediator complex has been extensively shown to regulate the levels of several protein-coding genes; however, its role in the regulation of miRNAs in humans remains unstudied so far. Here we show that MED1, a Mediator subunit in the Middle module of Mediator complex, is overexpressed in brea...

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Bibliographic Details
Main Authors: Neha Nagpal, Shivani Sharma, Sourobh Maji, Giorgio Durante, Manuela Ferracin, Jitendra K. Thakur, Ritu Kulshreshtha
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/7a50771a56c64067824c83dae9b9aa4e
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