Mycobacterium tuberculosis eis regulates autophagy, inflammation, and cell death through redox-dependent signaling.

The "enhanced intracellular survival" (eis) gene of Mycobacterium tuberculosis (Mtb) is involved in the intracellular survival of M. smegmatis. However, its exact effects on host cell function remain elusive. We herein report that Mtb Eis plays essential roles in modulating macrophage auto...

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Autores principales: Dong-Min Shin, Bo-Young Jeon, Hye-Mi Lee, Hyo Sun Jin, Jae-Min Yuk, Chang-Hwa Song, Sang-Hee Lee, Zee-Won Lee, Sang-Nae Cho, Jin-Man Kim, Richard L Friedman, Eun-Kyeong Jo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/7a68f703324c4101bda1cdde14254c6b
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