An integrative framework for Bayesian variable selection with informative priors for identifying genes and pathways.

The discovery of genetic or genomic markers plays a central role in the development of personalized medicine. A notable challenge exists when dealing with the high dimensionality of the data sets, as thousands of genes or millions of genetic variants are collected on a relatively small number of sub...

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Auteurs principaux: Bin Peng, Dianwen Zhu, Bradley P Ander, Xiaoshuai Zhang, Fuzhong Xue, Frank R Sharp, Xiaowei Yang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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R
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Accès en ligne:https://doaj.org/article/7a6bb25d881f4b0abb71673cb8f7b99c
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