Bone marrow lympho-myeloid malfunction in obesity requires precursor cell-autonomous TLR4

Obesity can affect bone marrow cell differentiation and the generation of myeloid and lymphoid cells. Here, the authors show that diet and obesity, as well as low-dose lipopolysaccharide, can alter Toll-like receptor 4 signaling bone marrow cells to skew the myeloid-lymphoid homeostasis in mice.

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Autores principales: Ailing Liu, Minhui Chen, Rashmi Kumar, Maja Stefanovic-Racic, Robert M. O’Doherty, Ying Ding, Willi Jahnen-Dechent, Lisa Borghesi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7a728719f6124ecf8609d688530588a3
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