Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations

Abstract Protein stability is a requisite in the field of biotechnology, cell biology and drug design. To understand effects of amino acid substitutions, computational models are preferred to save time and expenses. As a systemically important, highly abundant, stable protein, the knowledge of Cu/Zn...

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Autores principales: Vijay Kumar, Safikur Rahman, Hani Choudhry, Mazin A. Zamzami, Mohammad Sarwar Jamal, Asimul Islam, Faizan Ahmad, Md. Imtaiyaz Hassan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7a7aa2c0cdef490db3fa45664a3ddf86
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