Crystal structure and receptor-interacting residues of MYDGF — a protein mediating ischemic tissue repair

Crystal structure and receptor-interacting residues of MYDGF — a protein mediating ischemic tissue repair

Myeloid-derived growth factor (MYDGF) is an angiogenic growth factor with therapeutic potential for ischemic tissue repair and the receptor is still unknown. Here the authors present the crystal structure of human MYDGF and identify its functional epitope through mutagenesis studies.

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Bibliographic Details
Main Authors: Rebecca Ebenhoch, Abbas Akhdar, Marc R. Reboll, Mortimer Korf-Klingebiel, Priyanka Gupta, Julie Armstrong, Yining Huang, Lee Frego, Irina Rybina, John Miglietta, Anton Pekcec, Kai C. Wollert, Herbert Nar
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Science
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Online Access:https://doaj.org/article/7aa1821abf454c21a63dba52daa89da7
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https://doaj.org/article/7aa1821abf454c21a63dba52daa89da7

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