Streamlined asymmetric α-difunctionalization of ynones

Chiral ynones with an α-quaternary carbon are attractive synthetic building blocks for natural and pharmaceutical products. Here, the authors report an asymmetric α-difunctionalization of simple ynones, involving a gold-catalyzed step and yielding enantioenriched fluorinated quaternary stereocentres...

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Détails bibliographiques
Auteurs principaux: Siyu Peng, Zhaofeng Wang, Linxing Zhang, Xinhao Zhang, Yong Huang
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
Q
Accès en ligne:https://doaj.org/article/7aae27bc9ca542bbaead7d09124b167e
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