Streamlined asymmetric α-difunctionalization of ynones
Chiral ynones with an α-quaternary carbon are attractive synthetic building blocks for natural and pharmaceutical products. Here, the authors report an asymmetric α-difunctionalization of simple ynones, involving a gold-catalyzed step and yielding enantioenriched fluorinated quaternary stereocentres...
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| Main Authors: | , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
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| Subjects: | |
| Online Access: | https://doaj.org/article/7aae27bc9ca542bbaead7d09124b167e |
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