Machine learning modeling of genome-wide copy number alteration signatures reliably predicts IDH mutational status in adult diffuse glioma
Abstract Knowledge of 1p/19q-codeletion and IDH1/2 mutational status is necessary to interpret any investigational study of diffuse gliomas in the modern era. While DNA sequencing is the gold standard for determining IDH mutational status, genome-wide methylation arrays and gene expression profiling...
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Auteurs principaux: | , , , |
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Format: | article |
Langue: | EN |
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BMC
2021
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Accès en ligne: | https://doaj.org/article/7ae1cad55a3b4fa3835686acc7e09a84 |
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