Anticancer activity of oleanolic acid and its derivatives: Recent advances in evidence, target profiling and mechanisms of action
Oleanolic acid (OA, 3 β - hydroxyoleanolic acid-12-en-28-oic acid) is a pentacyclic triterpenoid present in many plants. As a new framework for development of semi synthetic triterpenoids, OA is of great significance in the discovery of anticancer drugs. Some of these derivatives, such as CDDO (2-cy...
Enregistré dans:
Auteurs principaux: | Zhong-Yuan Tang, Yang Li, Yu-Ting Tang, Xiao-Dong Ma, Ze-Yao Tang |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Elsevier
2022
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/7aef5f3ef6ec4b2bac39d66f5a2ffa09 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Oleanolic acid induces apoptosis and autophagy via the PI3K/AKT/mTOR pathway in AGS human gastric cancer cells
par: Jae-Han Lee, et autres
Publié: (2021) -
Effect of Ursolic and Oleanolic Acids on Lipid Membranes: Studies on MRSA and Models of Membranes
par: Sandrine Verstraeten, et autres
Publié: (2021) -
Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity
par: Khan MW, et autres
Publié: (2019) -
Plant-derived oleanolic acid ameliorates markers associated with non-alcoholic fatty liver disease in a diet-induced pre-diabetes rat model
par: Gamede M, et autres
Publié: (2019) -
Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo
par: Luo YL, et autres
Publié: (2016)