Porcine pancreatic ductal epithelial cells transformed with KRASG12D and SV40T are tumorigenic

Abstract We describe our initial studies in the development of an orthotopic, genetically defined, large animal model of pancreatic cancer. Primary pancreatic epithelial cells were isolated from pancreatic duct of domestic pigs. A transformed cell line was generated from these primary cells with onc...

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Autores principales: Katie L. Bailey, Sara B. Cartwright, Neesha S. Patel, Neeley Remmers, Audrey J. Lazenby, Michael A. Hollingsworth, Mark A. Carlson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7af2948a4821425da7bdc200f1faf33e
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