Ochratoxin A induces NLRP3 inflammasome-mediated pyroptosis via activation of ROS modulated by autophagy in vitro

Ochratoxin A (OTA), one of the major food contaminating mycotoxins, has been reported to cause renal fibrosis through pyroptosis, but the detailed mechanism of its nephrotoxicity remains to be further investigated. Autophagy can be seen in the physiological and pathological processes of the body, an...

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Autores principales: Kai Liu, Dongmei Yue, Xinru Mao, Hu Li, Jie Qu, Shuiping Liu, Viktor I. Korolchuk, Yunhuan Liu, Fang Gan, Cuiling Pan, Kehe Huang, Xingxiang Chen
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/7afbedaff66f44c0a7ad47744c03c267
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