Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma.

Epigenetic modifications are important early events during carcinogenesis. In particular, hypermethylation of CpG islands in the promoter region of tumor suppressor genes is a well-known mechanism of gene silencing that contributes to cancer development and progression. Tissue factor pathway inhibit...

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Autores principales: Serena Ferraresso, Silvia Bresolin, Arianna Aricò, Stefano Comazzi, Maria Elena Gelain, Fulvio Riondato, Luca Bargelloni, Laura Marconato, Geertruy te Kronnie, Luca Aresu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/7b0410274e524aa69afd23d7fc13b608
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